Hemodialysis-Associated Infections: Treatment with Cephapirin

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1978 English Publisher:American Society for MicrobiologyJournal:Antimicrobial Agents and Chemotherapy, volume 13, pages 4-6 (issn: 0066-4804, eissn: 1098-6596,

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Authors: S J, Berman; W H, Boughton; J G, Sugihara; E G, Wong; A W, Siemsen;

doi: 10.1128/aac.13.1.4

pmid: 343713

pmc: PMC352175

Hemodialysis-Associated Infections: Treatment with Cephapirin

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Abstract

Large doses of cephapirin (50 mg/kg) administered during the first and last half hours of routine hemodialysis produced effective antimicrobial serum concentrations for 48 h. Repetitive administration during five successive hemodialysis sessions did not result in accumulation or accelerated metabolism of cephapirin. Ten infectious episodes in nine patients were treated in this manner with good clinical results and no toxicity.

Related Organizations

University of Hawaiʻi Sea Grant
United States
University of Hawaii System
United States
University of Hawaii at Manoa
United States
St. Francis Hospital
United States

Keywords

Cephapirin, Renal Dialysis, Humans, Staphylococcal Infections, Escherichia coli Infections, Cephalosporins

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