Effect of Antibiotics on Chemotaxis of Human Leukocytes

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1977 English Publisher:American Society for MicrobiologyJournal:Antimicrobial Agents and Chemotherapy, volume 11, pages 580-584 (issn: 0066-4804, eissn: 1098-6596,

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Authors: A, Forsgren; D, Schmeling;

doi: 10.1128/aac.11.4.580

pmid: 856009

pmc: PMC352031

Effect of Antibiotics on Chemotaxis of Human Leukocytes

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Abstract

The effect of 20 different antibiotics on chemotaxis by human neutrophils was studied. Human leukocytes incubated with chloramphenicol, rifampin, sodium fusidate, and tetracyclines in vitro showed markedly depressed migration. The mechanisms by which these antibiotics affect leukotaxis are discussed.

Related Organizations

Lund University
Sweden

Keywords

Chemotaxis, Leukocyte, Chloramphenicol, Neutrophils, Tetracyclines, Humans, Rifampin, Fusidic Acid, Anti-Bacterial Agents

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