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Antimicrobial Agents and Chemotherapy
Article . 2023 . Peer-reviewed
License: CC BY
Data sources: Crossref
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PubMed Central
Other literature type . 2023
License: CC BY
Data sources: PubMed Central
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Clinical Efficacy and Safety of a Novel Antifungal, Fosmanogepix, in Patients with Candidemia Caused by Candida auris : Results from a Phase 2 Trial

Authors: Jose A. Vazquez; Peter G. Pappas; Kenneth Boffard; Fathima Paruk; Paul A. Bien; Margaret Tawadrous; Eric Ople; +3 Authors

Clinical Efficacy and Safety of a Novel Antifungal, Fosmanogepix, in Patients with Candidemia Caused by Candida auris : Results from a Phase 2 Trial

Abstract

Fosmanogepix (FMGX), a novel antifungal available in intravenous (IV) and oral formulations, has broad-spectrum activity against pathogenic yeasts and molds, including fungi resistant to standard of care antifungals. This multicenter, open-label, single-arm study evaluated FMGX safety and efficacy for treatment of candidemia and/or invasive candidiasis caused by Candida auris .

Country
South Africa
Keywords

Intensive care unit (ICU), SDG-17: Partnerships for the goals, Male, SDG-03: Good health and well-being, Antifungal Agents, APX001, Fosmanogepix (FMGX), 610, Microbial Sensitivity Tests, Health sciences articles SDG-17, Gwt1 inhibitor, 616, Humans, Experimental Therapeutics, Candidiasis, Invasive, Fosmanogepix, Health sciences articles SDG-03, Candidiasis, Candidemia, Candida auris, Treatment Outcome, Female, Isocyanates

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    57
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 1%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
57
Top 1%
Top 10%
Top 1%
Green
hybrid