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Overview of Molecular Diagnostics in Multiple-Drug-Resistant Organism Prevention: Focus on Multiple-Drug-Resistant Gram-Negative Bacterial Organisms

Name: Overview of Molecular Diagnostics in Multiple-Drug-Resistant Organism Prevention: Focus on Multiple-Drug-Resistant Gram-Negative Bacterial Organisms
Keywords: 3. Good health

descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Other literature type 01 Jan 2016Publisher:American Society of Microbiology

Authors: Daniel J. Diekema; Kaede V. Sullivan;

doi: 10.1128/9781555819071.ch17

Overview of Molecular Diagnostics in Multiple-Drug-Resistant Organism Prevention: Focus on Multiple-Drug-Resistant Gram-Negative Bacterial Organisms

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Abstract

The combination of increasing rates of antibiotic resistance and the decreasing pace of new antibiotic development has become an urgent public health crisis (1). Multiple-drug-resistant bacterial organisms (MDROs) have now become common causes of health care-associated infection (HAI), the most prevalent being methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), and a variety of multiple-drug-resistant Gram-negative rods (MDR-GNRs; organisms that are resistant to most, if not all, available antibiotic classes through myriad mechanisms, including production of β-lactamases with increasingly broad activity) (2–4).

Related Organizations

University of Pennsylvania
United States
Roy J. and Lucille A. Carver College of Medicine
United States

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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
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