Powered by OpenAIRE graph
Found an issue? Give us feedback
Science s STKEarrow_drop_down
Science s STKE
Article . 2000 . Peer-reviewed
Data sources: Crossref
Claim

To B Cell, or Not to B Cell

descriptionPublicationkeyboard_double_arrow_right Article 30 May 2000 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science's STKE, volume 2,000 (eissn: 1525-8882, Copyright policy )

doi: 10.1126/stke.2000.34.tw7

To B Cell, or Not to B Cell

Abstract

The transcription factor PU.1 is essential in B cell and macrophage development and proliferation. DeKoter and Singh show that the level of expression of PU.1 can control which cell fate will result. At low levels, PU.1 protein caused precursor cells to differentiate into B lymphocytes; whereas at high levels of PU.1, the same cells differentiated into macrophages. DeKoter, R.P., and Singh, H. (2000) Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 288 : 1439-1441. [Abstract] [Full Text]

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Upload OA version
Are you the author of this publication? Upload your Open Access version to Zenodo!
It’s fast and easy, just two clicks!
uploadUpload now