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TRPML1ng on sparks

descriptionPublicationkeyboard_double_arrow_right Article 23 Jun 2020 United States English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science Signaling, volume 13 (issn: 1945-0877, eissn: 1937-9145, Copyright policy )Funded by:NIH | Tuning L-Type Ca Channel ..., NIH | Coupling of vascular CaV1..., NIH | A single amino acid in Ca... +1 projects
Authors: Madeline Nieves-Cintron; Luis F. Santana; Manuel F. Navedo;

doi: 10.1126/scisignal.abc0993

pmid: 32576679

pmc: PMC7384335

TRPML1ng on sparks

Abstract

The lysosomal channel TRPML1 acts as the trigger for Ca 2+ sparks that promote arterial relaxation (Thakore et al. , in 23 June 2020 issue).

Country
United States
Related Organizations
Keywords

Myocytes, 1.1 Normal biological development and functioning, Myocytes, Smooth Muscle, 610, Ryanodine Receptor Calcium Release Channel, Biological Sciences, Cardiovascular, Muscle, Smooth, Vascular, Smooth Muscle, Vascular, Biochemistry and cell biology, Muscle, Calcium, Biochemistry and Cell Biology, Smooth, Calcium Signaling

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 3
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Top 10%
Average
Average
Green
bronze