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Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation

Authors: Nathalie Niyonzima; Jubayer Rahman; Natalia Kunz; Erin E. West; Tilo Freiwald; Jigar V. Desai; Nicolas S. Merle; +30 Authors

Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation

Abstract

Mitochondrial C5aR1 signaling is required for proinflammatory macrophage activity during crystal-induced sterile inflammation.

Keywords

Inflammation, Mice, Inbred C57BL, Mice, Knockout, Mice, Macrophages, Interleukin-1beta, Animals, Humans, Receptor, Anaphylatoxin C5a, Cell Line

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    influence
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Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
128
Top 1%
Top 10%
Top 1%
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