The Biological Weapons Convention turned 50 this year. Since 1975, the intent of this international treaty has been to prohibit the development, production, and stockpiling of biological and toxin weapons. Global commitment to these objectives is reflected by the treaty’s total membership of 188 states. However, member states have thus far been unable to raise strong barriers against illicit bioweapons development. With rapid advancements in science and technology and the rise of biological weapons disinformation, improvements of the Convention are urgently needed. One way to reinforce the treaty is to consider an inspection mechanism that aims to disrupt illicit programs rather than detect them.