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Dosing time matters

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type , Preprint 15 Mar 2019 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science, volume 365, pages 547-549 (issn: 0036-8075, eissn: 1095-9203, Copyright policy )Funded by:NIH | Circadian Rhythms and Int..., NIH | Overcoming bias and unwan..., NIH | Functional Genomics of Ma... +1 projects
Authors: Ruben, Marc D.; Smith, David F.; FitzGerald, Garret A.; Hogenesch, John B.;

doi: 10.1126/science.aax7621 , 10.1101/570119

pmid: 31395773

pmc: PMC8011856

Dosing time matters

Abstract

Circadian precision medicine may supplement genetic precision to improve drug action

Related Organizations
Keywords

Time Factors, Dose-Response Relationship, Drug, Drug Chronotherapy, Humans, Pharmacokinetics, Precision Medicine, Drug Administration Schedule, Circadian Rhythm

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 215
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 0.1%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
215
Top 1%
Top 10%
Top 0.1%
Green
bronze