Mutation of a bHLH transcription factor allowed almond domestication
Copyright policy )Mutation of a bHLH transcription factor allowed almond domestication
How to make almonds palatable The domesticated almond tree has been feeding humans for millennia. Derivation from the wild, bitter, and toxic almond required loss of the cyanogenic diglucoside amygdalin. Sánchez-Pérez et al. sequenced the almond genome and analyzed the genomic region responsible for this shift. The key change turned out to be a point mutation in a transcription factor that regulates production of P450 monooxygenases in the biosynthetic pathway for the toxic compound. Science , this issue p. 1095
- National Research Council Italy
- KOBENHAVNS UNIVERSITET Denmark
- University of Copenhagen Denmark
- University of Foggia Italy
- University of Bari Aldo Moro Italy
Basic Helix-Loop-Helix Proteins, Transcription, Genetic, Protein Conformation, Phenylalanine, Amygdalin, Almond, *, Domestication, domestication, Cytochrome P-450 Enzyme System, Gene Expression Regulation, Plant, Leucine, Point Mutation, genome, transcription factor, Plant Proteins, Multidisciplinary, Prunus dulcis, Amino Acid Substitution, Multigene Family, Taste, mutation, Protein Multimerization
Basic Helix-Loop-Helix Proteins, Transcription, Genetic, Protein Conformation, Phenylalanine, Amygdalin, Almond, *, Domestication, domestication, Cytochrome P-450 Enzyme System, Gene Expression Regulation, Plant, Leucine, Point Mutation, genome, transcription factor, Plant Proteins, Multidisciplinary, Prunus dulcis, Amino Acid Substitution, Multigene Family, Taste, mutation, Protein Multimerization
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