Functionally diverse type V CRISPR-Cas systems
Copyright policy )Functionally diverse type V CRISPR-Cas systems
Additional, diverse CRISPR systems CRISPR systems have been revolutionizing molecular biology. Mining the metagenomic database, Yan et al. systematically discovered additional subtypes of type V CRISPR-Cas systems. The additional Cas12 effectors displayed a range of activities, including target and collateral cleavage of single-stranded RNA and DNA, as well as double-stranded DNA nicking and cleavage. These diverse nuclease activities suggest how an ancient transposase may have evolved into various type V effectors and expand the nucleic acid detection and genome-editing toolbox. Science , this issue p. 88
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Deoxyribonucleases, Ribonucleases, Escherichia coli, Nucleic Acid Conformation, DNA, CRISPR-Cas Systems, RNA, Guide, CRISPR-Cas Systems, Databases, Protein, Gene Library
Deoxyribonucleases, Ribonucleases, Escherichia coli, Nucleic Acid Conformation, DNA, CRISPR-Cas Systems, RNA, Guide, CRISPR-Cas Systems, Databases, Protein, Gene Library
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