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A Morbillivirus that Caused Fatal Fisease in Horses and Humans

Authors: Murray, K; Selleck, P; Hooper, P; Hyatt, A; Gould, A; Gleeson, L; Westbury, H; +4 Authors

A Morbillivirus that Caused Fatal Fisease in Horses and Humans

Abstract

A morbillivirus has been isolated and added to an increasing list of emerging viral diseases. This virus caused an outbreak of fatal respiratory disease in horses and humans. Genetic analyses show it to be only distantly related to the classic morbilliviruses rinderpest, measles, and canine distemper. When seen by electron microscopy, viruses had 10- and 18-nanometer surface projections that gave them a "double-fringed" appearance. The virus induced syncytia that developed in the endothelium of blood vessels, particularly the lungs.

Country
Australia
Keywords

Adult, Male, Veterinary medicine, Molecular Sequence Data, Matrix Protein, Comparative Sequence-Analysis, Rinderpest Virus, Kidney, Gene, Veterinary medicine of special organs, Disease Outbreaks, Amino-Acid-Sequences, regions and systems, Pregnancy, Chlorocebus aethiops, Animals, Humans, Amino Acid Sequence, Horses, Lung, Respiratory Tract Infections, Base Sequence, Middle Aged, Veterinary virology, Morbillivirus, Phocine Distemper Virus, Paramyxoviruses, Female, Horse Diseases, Respiratory Syncytial Virus, Molecular-Cloning, Queensland, Nucleotide-Sequence, Morbillivirus Infections

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Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
674
Top 0.1%
Top 0.1%
Top 1%
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