Ivermectin: A Potent New Antiparasitic Agent
Copyright policy )Ivermectin: A Potent New Antiparasitic Agent
Ivermectin is the 22,23-dihydro derivative of avermectin B 1 , a macrocyclic lactone produced by an actinomycete, Streptomyces avermitilis . It is active at extremely low dosage against a wide variety of nematode and arthropod parasites, apparently by virtue of its action on the mediation of neurotransmission by γ-aminobutyric acid. It is now in commercial use in various countries for the treatment and control of parasites in cattle, horses, and sheep, and is expected to become available for use in swine and dogs. Since studies with the drug in man are in a preliminary stage, it is not yet known whether ivermectin will be useful in human medicine.
- Merck & Co. United States
Anthelmintics, Insecticides, Ivermectin, Synaptic Transmission, Streptomyces, Lactones, Structure-Activity Relationship, Animals, Humans, Nematode Infections, Arthropods
Anthelmintics, Insecticides, Ivermectin, Synaptic Transmission, Streptomyces, Lactones, Structure-Activity Relationship, Animals, Humans, Nematode Infections, Arthropods
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).769 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 0.1% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 0.1% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 1%
Citations provided by BIP!Popularity provided by BIP!