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pmid: 6163215
A secondary structure model for 16 S ribosomal RNA which is based on available chemical, enzymatic, and comparative sequence data shows good agreement between constraints dictated by the model and a wide variety of experimental observations. The four major structural domains created by the base-pairing scheme correspond closely to RNA fragments isolated after nuclease digestion in the presence of bound ribosomal proteins. Functionally important sites appear to be located in unpaired regions and are phylogenetically highly conserved.
Ribosomal Proteins, Binding Sites, Base Sequence, Hydrogen Bonding, Biological Evolution, Substrate Specificity, RNA, Bacterial, Ribonucleases, RNA, Ribosomal, Escherichia coli, Nucleic Acid Conformation, Ribosomes, Protein Binding
Ribosomal Proteins, Binding Sites, Base Sequence, Hydrogen Bonding, Biological Evolution, Substrate Specificity, RNA, Bacterial, Ribonucleases, RNA, Ribosomal, Escherichia coli, Nucleic Acid Conformation, Ribosomes, Protein Binding
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 461 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 1% | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 0.1% | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 1% |