Calcitonin: Inhibitory Effect on Eating in Rats
Copyright policy )Calcitonin: Inhibitory Effect on Eating in Rats
Subcutaneous and intracerebral injections of calcitonin inhibited feeding in rats. The anorectic activity of calcitonin was destroyed by exposing the hormone to heat, trypsin, or hydrogen peroxide. Calcitonin did not produce a conditioned taste aversion to saccharin, and maximum inhibition of feeding occurred 4.5 to 8.3 hours after subcutaneous administration. It is concluded that calcitonin inhibits feeding by acting directly on the central nervous system.
- National Institutes of Health United States
- National Institute of Mental Health United States
- St. Elizabeth's Medical Center United States
Calcitonin, Dose-Response Relationship, Drug, Depression, Chemical, Animals, Brain, Feeding Behavior, Diuresis, Injections, Intraventricular, Rats
Calcitonin, Dose-Response Relationship, Drug, Depression, Chemical, Animals, Brain, Feeding Behavior, Diuresis, Injections, Intraventricular, Rats
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