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When beige is not boring

Authors: Wei Wong;

When beige is not boring

Abstract

Metabolism Shifting energy-storing white adipocytes or their progenitors into energy-burning beige adipocytes could be a strategy to combat obesity. Working in mice, Babaei et al. found that transient inflammation induced adipocyte progenitors to differentiate into beige adipocytes (see the Focus by Sun et al. ). Unfortunately, mitophagy causes beige adipocytes to revert to white adipocytes in the absence of “browning” stimuli. Lu et al. found that a browning stimulus prevented the mitochondrial recruitment of the mitophagy factor Parkin and that Parkin-deficient mice maintained beige fat upon stimulus withdrawal (see the Focus by Sarraf and Youle). Sci. Signal. 11 , eaap8526, eaai7838; see also eaat1082, eaat3192 (2018).

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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