Recognizing danger signals

Valda Vinson

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Article . 2018 . Peer-reviewed

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https://dx.doi.org/10.1126/sci...

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Recognizing danger signals

descriptionPublicationkeyboard_double_arrow_right Article 15 Feb 2018 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science, volume 359, pages 756.5-757 (issn: 0036-8075, eissn: 1095-9203,

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Authors: Valda Vinson;

doi: 10.1126/science.359.6377.756-e

Recognizing danger signals

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Abstract

Structural Immunology In the classical complement pathway, the C1 initiation complex binds to danger patterns on the surface of microbes or damaged host cells and triggers an immune response. Immunoglobulin G (IgG) antibodies form hexamers on cell surfaces that have high avidity for the C1 complex.

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