Splicing of Messenger RNA Precursors
Copyright policy )Splicing of Messenger RNA Precursors
A general mechanism for the splicing of nuclear messenger RNA precursors in eukaryotic cells has been widely accepted. This mechanism, which generates lariat RNAs possessing a branch site, seems related to the RNA-catalyzed reactions of self-splicing introns. The splicing of nuclear messenger RNA precursors involves the formation of a multicomponent complex, the spliceosome. This splicing body contains at least three different small nuclear ribonucleoprotein particles (snRNPs), U2, U5, and U4 + U6. A complex containing precursor RNA and the U2 snRNP particle is a likely intermediate in the formation of the spliceosome.
- Massachusetts Institute of Technology United States
Models, Genetic, Base Sequence, RNA Splicing, Nucleic Acid Precursors, Saccharomyces cerevisiae, Ribonucleoproteins, Small Nuclear, Introns, Eukaryotic Cells, Ribonucleoproteins, RNA, Ribosomal, Protein Biosynthesis, RNA, Small Nuclear, Mutation, Tetrahymena, RNA Precursors, RNA, Heterogeneous Nuclear, Animals, RNA, Catalytic, RNA, Messenger
Models, Genetic, Base Sequence, RNA Splicing, Nucleic Acid Precursors, Saccharomyces cerevisiae, Ribonucleoproteins, Small Nuclear, Introns, Eukaryotic Cells, Ribonucleoproteins, RNA, Ribosomal, Protein Biosynthesis, RNA, Small Nuclear, Mutation, Tetrahymena, RNA Precursors, RNA, Heterogeneous Nuclear, Animals, RNA, Catalytic, RNA, Messenger
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