The Granulocyte-Macrophage Colony-Stimulating Factors
Copyright policy )The Granulocyte-Macrophage Colony-Stimulating Factors
The granulocyte-macrophage colony-stimulating factors are well-characterized specific glycoproteins that interact to control the production, differentiation, and function of two related white cell populations of the blood, the granulocytes and monocyte-macrophages. Widely produced in the body, these regulators probably play an important role in resistance to infections. The proliferation of myeloid leukemia cells remains dependent on stimulation by colony-stimulating factors, although one of them also has the ability to suppress leukemic populations by inducing terminal differentiation.
- Royal Melbourne Hospital Australia
- Melbourne Health Australia
- Walter and Eliza Hall Institute of Medical Research Australia
Cell Survival, Bone Marrow Cells, Receptors, Cell Surface, Cell Line, Mice, Colony-Stimulating Factors, Species Specificity, Sequence Homology, Nucleic Acid, Receptors, Colony-Stimulating Factor, Animals, Humans, Cloning, Molecular, Macrophages, Chromosome Mapping, Cell Differentiation, DNA, Hematopoietic Stem Cells, Hematopoiesis, Molecular Weight, Leukemia, Myeloid, Acute, Leukemia, Myeloid, Cell Division, Granulocytes
Cell Survival, Bone Marrow Cells, Receptors, Cell Surface, Cell Line, Mice, Colony-Stimulating Factors, Species Specificity, Sequence Homology, Nucleic Acid, Receptors, Colony-Stimulating Factor, Animals, Humans, Cloning, Molecular, Macrophages, Chromosome Mapping, Cell Differentiation, DNA, Hematopoietic Stem Cells, Hematopoiesis, Molecular Weight, Leukemia, Myeloid, Acute, Leukemia, Myeloid, Cell Division, Granulocytes
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