Chemical Diversity in RNA Cleavage
Copyright policy )Chemical Diversity in RNA Cleavage
It was quite a shock when it was first discovered that RNA can perform catalysis, sometimes every bit as efficiently as an enzyme. In his Perspective, [Westhof][1] now describes new evidence ([ Perrotta et al. ][2]) that so-called ribozymes can perform base-catalysis without the assistance of a metal ion. In an early world containing only RNA molecules, the possibilities for chemical reactions were wider than we thought. [1]: http://www.sciencemag.org/cgi/content/full/286/5437/61 [2]: http://www.sciencemag.org/cgi/content/short/286/5437/123
Cytosine, Mutagenesis, Imidazoles, Point Mutation, RNA, Catalytic, Hepatitis Delta Virus, Hydrogen-Ion Concentration, Base Pairing, Catalysis
Cytosine, Mutagenesis, Imidazoles, Point Mutation, RNA, Catalytic, Hepatitis Delta Virus, Hydrogen-Ion Concentration, Base Pairing, Catalysis
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