Polymorphism of Human Constitutive Heterochromatin

descriptionPublicationkeyboard_double_arrow_right Article 12 Nov 1971 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science, volume 174, pages 702-704 (issn: 0036-8075, eissn: 1095-9203,

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Authors: A P, Craig-Holmes; M W, Shaw;

doi: 10.1126/science.174.4010.702

pmid: 5123418

Polymorphism of Human Constitutive Heterochromatin

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Abstract

Genetic polymorphism has been demonstrated in man for many characteristics including blood groups, serum proteins, tissue enzymes, and hemoglobins. A class of chromosomal polymorphism involving constitutive heterochromatin has now been found. Through the use of a special technique that permits visualization of heterochromatin, seven heterochromatin variants have been found among four individuals. These results suggest a very high frequency of variability of heterochromatin in the population.

Related Organizations

The University of Texas Health Science Center at Houston
United States

Keywords

Chromosomes, Human, 6-12 and X, Polymorphism, Genetic, Chromosomes, Human, 19-20, Chromosomes, Human, 1-3, DNA, Nucleic Acid Denaturation, Heterochromatin, Chromosomes, Human, 21-22 and Y, Methods, Nucleic Acid Renaturation, Humans, Lymphocytes, Chromosomes, Human, 13-15, Chromosomes, Human, 16-18

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