Structure of RNA in Ribosomes

descriptionPublicationkeyboard_double_arrow_right Article 09 Oct 1970 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science, volume 170, pages 171-173 (issn: 0036-8075, eissn: 1095-9203,

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Authors: K A, Hartman; J, Amaya; E M, Schachter;

doi: 10.1126/science.170.3954.171

pmid: 4917385

Structure of RNA in Ribosomes

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Abstract

The 50 S and 30 S ribosomes and 23 S and 16 S RNA were hydrolyzed with ribonuclease A. The rate constants and number of fragments produced were determined for each reaction. The conformation of 23 S RNA changes when the RNA is extracted from the ribosome. Specific regions of the RNA in 50 S and 30 S ribosomes are protected from hydrolysis by the ribosomal proteins.

Related Organizations

University of Rhode Island
United States

Keywords

Molecular Weight, Kinetics, RNA, Bacterial, Ribonucleases, Bacterial Proteins, Escherichia coli, RNA, Electrophoresis, Disc, Ribosomes

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