Neuroglia: Gliosis and Focal Epilepsy

descriptionPublicationkeyboard_double_arrow_right Article 27 Feb 1970 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science, volume 167, pages 1,252-1,253 (issn: 0036-8075, eissn: 1095-9203,

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Authors: D A, Pollen; M C, Trachtenberg;

doi: 10.1126/science.167.3922.1252

pmid: 4983671

Neuroglia: Gliosis and Focal Epilepsy

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Abstract

Normal neuroglial cells buffer the extracellular space around neurons and presynaptic terminals against increases in potassium ions. Epileptic foci resulting from brain injury are characterized by areas of intense fibrillary gliosis bordering neuronal tissue. The known pathological changes that occur in gliosis may impair glial control of extracellular potassium ions and lead to excessively excitable neuronal border regions.

Related Organizations

Harvard University
United States
Massachusetts General Hospital
United States

Keywords

Cicatrix, Potassium, Epilepsies, Partial, Gliosis, Epilepsy, Post-Traumatic, Extracellular Space, Neuroglia

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