Heterogeneity of Human Ceruloplasmin

descriptionPublicationkeyboard_double_arrow_right Article 25 Mar 1960 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science, volume 131, pages 930-932 (issn: 0036-8075, eissn: 1095-9203,

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Authors: A G, MORELL; I H, SCHEINBERG;

doi: 10.1126/science.131.3404.930

pmid: 14424028

Heterogeneity of Human Ceruloplasmin

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Abstract

Subfractionation of purified human ceruloplasmin, prepared from plasma of 9109 donors, has been carried out by chromatography on columns of diethylaminoethyl cellulose and hydroxylapatite. Electrophoretic analyses of these subfractions on starch gels, at p H 8.5 and 5.7, reveal the presence of at least four ceruloplasmins, two of which appear to differ in histidine content.

Related Organizations

Yeshiva University
United States
Albert Einstein College of Medicine
United States

Keywords

Durapatite, Ceruloplasmin, Histidine, Serum Globulins, Starch, Cellulose

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