Genetic Characteristics of the HeLa Cell

descriptionPublicationkeyboard_double_arrow_right Article 30 Jan 1976 United Kingdom English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science, volume 191, pages 392-394 (issn: 0036-8075, eissn: 1095-9203,

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Authors: Hsu, S; Schacter, B; Delaney, N; Miller, T; McKusick, V; Kennett, R; Bodmer, J; +2 Authors

doi: 10.1126/science.1246620

pmid: 1246620

Genetic Characteristics of the HeLa Cell

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Abstract

The genotype of the patient Henrietta Lacks from whose cervical carcinoma the HeLa cell was derived was deduced from the phenotypes of her husband and children, and from studies of the HeLa cell. Hemizygous expression of glucose-6-phosphate dehydrogenase in HeLa, together with the deduced heterozygosity of Mrs. Lacks, is consistent with clonal origin of her neoplasm.

Country

United Kingdom

Related Organizations

Johns Hopkins Medicine
United States
Johns Hopkins University School of Medicine
United States
University of Oxford
United Kingdom

Keywords

Male, Isoantigens, Sex Chromosomes, Genotype, Glucosephosphate Dehydrogenase, Pedigree, Phenotype, HLA Antigens, Humans, Female, HeLa Cells

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