Ribozyme-Catalyzed Transcription of an Active Ribozyme

descriptionPublicationkeyboard_double_arrow_right Article 08 Apr 2011 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science, volume 332, pages 209-212 (issn: 0036-8075, eissn: 1095-9203,

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Authors: Aniela, Wochner; James, Attwater; Alan, Coulson; Philipp, Holliger;

doi: 10.1126/science.1200752

pmid: 21474753

Ribozyme-Catalyzed Transcription of an Active Ribozyme

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Abstract

A functional RNA has been synthesized by an RNA enzyme from mononucleotide building blocks.

Related Organizations

MRC Laboratory of Molecular Biology
United Kingdom
Medical Research Council
United Kingdom

Keywords

Base Sequence, Transcription, Genetic, Templates, Genetic, RNA-Dependent RNA Polymerase, Mutation, Biocatalysis, Nucleic Acid Conformation, RNA, RNA, Catalytic, Directed Molecular Evolution, Selection, Genetic, Genetic Engineering

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