Genetic Mapping in Human Disease
Copyright policy )Genetic Mapping in Human Disease
Genetic mapping provides a powerful approach to identify genes and biological processes underlying any trait influenced by inheritance, including human diseases. We discuss the intellectual foundations of genetic mapping of Mendelian and complex traits in humans, examine lessons emerging from linkage analysis of Mendelian diseases and genome-wide association studies of common diseases, and discuss questions and challenges that lie ahead.
- Harvard University United States
- Massachusetts General Hospital United States
- Massachusetts Institute of Technology United States
- Whitehead Institute for Biomedical Research United States
- Broad Institute United States
Genotype, Genetic Linkage, Genome, Human, Chromosome Mapping, Physical Chromosome Mapping, Polymorphism, Single Nucleotide, Linkage Disequilibrium, Quantitative Trait, Heritable, Risk Factors, Mutation, Humans, Disease, Cloning, Molecular, Selection, Genetic, Genome-Wide Association Study
Genotype, Genetic Linkage, Genome, Human, Chromosome Mapping, Physical Chromosome Mapping, Polymorphism, Single Nucleotide, Linkage Disequilibrium, Quantitative Trait, Heritable, Risk Factors, Mutation, Humans, Disease, Cloning, Molecular, Selection, Genetic, Genome-Wide Association Study
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