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Claim

Cosmc deficiency causes spontaneous autoimmunity by breaking B cell tolerance

descriptionPublicationkeyboard_double_arrow_right Article 08 Oct 2021 United States English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science Advances, volume 7 (eissn: 2375-2548, Copyright policy )Funded by:NIH | The Tumor Antigens Tn and...
Authors: Junwei Zeng; Rajindra P. Aryal; Kathrin Stavenhagen; Chi Luo; Renyan Liu; Xiaohui Wang; Jiaxuan Chen; +6 Authors

doi: 10.1126/sciadv.abg9118

pmid: 34613773

pmc: PMC8494437

Cosmc deficiency causes spontaneous autoimmunity by breaking B cell tolerance

Abstract

O-glycans on B cell glycoproteins controlled by X-linked Cosmc are required for B cell tolerance and preventing autoimmunity.

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United States
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Keywords

cosmc, B cells, autoimmunity, 610, Biomedicine and Life Sciences

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 11
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
11
Top 10%
Average
Top 10%
Green
gold