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High-purity production and precise editing of DNA base editing ribonucleoproteins

descriptionPublicationkeyboard_double_arrow_right Article 27 Aug 2021 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science Advances, volume 7 (eissn: 2375-2548, Copyright policy )
Authors: Hyeon-Ki Jang; Dong Hyun Jo; Seu-Na Lee; Chang Sik Cho; You Kyeong Jeong; Youngri Jung; Jihyeon Yu; +3 Authors

doi: 10.1126/sciadv.abg2661

pmid: 34452911

pmc: PMC8397273

High-purity production and precise editing of DNA base editing ribonucleoproteins

Abstract

Cytosine and adenine base editor ribonucleoproteins show precise base editing with reduced DNA and RNA off-target effects.

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Keywords

Gene Editing, Cytosine, Mice, Ribonucleoproteins, Animals, RNA, DNA, CRISPR-Cas Systems, Research Articles

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 75
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 1%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
75
Top 1%
Top 10%
Top 1%
Green
gold
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