
doi: 10.1124/pr.58.4.6
pmid: 17132852
The nuclear receptors of the NR1H and NR1I subgroups include the constitutive androstane receptor, pregnane X receptor, farnesoid X receptors, liver X receptors, and vitamin D receptor. The newly emerging functions of these related receptors are under the control of metabolic pathways, including metabolism of xenobiotics, bile acids, cholesterol, and calcium. This review summarizes results of structural, pharmacologic, and genetic studies of these receptors.
Receptors, Steroid, Pregnane X Receptor, Receptors, Cytoplasmic and Nuclear, Orphan Nuclear Receptors, DNA-Binding Proteins, Terminology as Topic, Mutation, Animals, Humans, Receptors, Calcitriol, Receptor, Farnesoid X-Activated, Constitutive Androstane Receptor, Liver X Receptors, Transcription Factors
Receptors, Steroid, Pregnane X Receptor, Receptors, Cytoplasmic and Nuclear, Orphan Nuclear Receptors, DNA-Binding Proteins, Terminology as Topic, Mutation, Animals, Humans, Receptors, Calcitriol, Receptor, Farnesoid X-Activated, Constitutive Androstane Receptor, Liver X Receptors, Transcription Factors
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