Transient acoustic signals were recently detected at the Main Endeavour Hydrothermal Vent Field which are believed to be generated by both geological and biological sources, including vent chimney collapse, impulsive geological signals, fish grunts, and snapping. These signals provide an opportunity for long-term passive acoustic monitoring of hydrothermal vent activity and ecology. This method offers advantages of longevity and robustness compared with other monitoring techniques, as the sensor can remain a safe distance away from the high-temperature, caustic vent fluid. Utilizing recordings from a bottom-mounted hydrophone on Ocean Networks Canada’s NEPTUNE observatory, a detector was implemented to identify and classify these signals in more than one year of acoustic data after 2016. While only a single hydrophone is available at this site, an array of three seismic accelerometers also on the NEPTUNE observatory was used to localize transient events when sufficient signal-to-noise ratio was available to provide confidence in the location estimate. Correlation of the transient sounds with seismic activity at the vent field was also evaluated, suggesting that passive acoustic monitoring can augment seismic records to provide additional information regarding geological activity at hydrothermal vent sites.