A method of and a system for active vibration control of an extended mechanical structure having a point or region at which unwanted vibrations are to be reduced or suppressed, wherein a plurality of uni-axial inertial actuators (4, 5) are disposed to act on a rigid intermediate part such as a flange (1) attached to the point or region of the structure. The actuators may be controlled by an electronic controller (35, FIG. 3) to which are fed control signals from accelerometer sensors (27, 28) adjacent the flange (11).