The effect of ultrasonic cavitation on protein antigenicity

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 1976 English Publisher:Acoustical Society of America (ASA)Journal:The Journal of the Acoustical Society of America, volume 59, pages 1,513-1,514 (issn: 0001-4966, eissn: 1520-8524,

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Authors: J H, Edwards; C J, James; W T, Coakley; R C, Brown;

doi: 10.1121/1.381003

pmid: 939885

The effect of ultrasonic cavitation on protein antigenicity

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Abstract

The antigenicity and enzyme activity of dilute solutions of RNAse exposed to ultrasonic cavitation have been measured as a function of exposure time. The rate of decrease of antigenicity was one-eighth of the rate of enzyme activity loss. The implication of the results for the use of ultrasound in antigen preparation is discussed. Subject Classification: [43]80.40.

Related Organizations

Medical Research Council
United Kingdom
Cardiff and Vale University Health Board
United Kingdom
University Hospital Llandough
United Kingdom
Cardiff University
United Kingdom

Keywords

Ribonucleases, Ultrasonics, Antigens, Endonucleases

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