Acoustical design challenges in hospitals are providing better communication to reduce medical errors and speech privacy that has also become a legal issue according to the Health Information Portability and Accountability Act (HIPAA). Some industrial products performance criteria are being exaggerated in the claims as solutions for better room acoustics of healthcare spaces. This study demonstrates an acoustical quality improvement of a patient care-unit environment. Building regulation codes, health service activities, space openness, and confined space layout are used as parametric studies for effective room acoustics design solutions. Current techniques in computer simulation are utilized along with field measurements to localize sources and identify critical elements that create the most impact. Acoustical treatments with characteristics adopting the industrial products are applied within the architectural elements including adjustable hung curtains, furniture, and art displays on wall surfaces. The improvement results are subjectively evaluated within VR environment of selected scenes to obtain real time spatial experience given the auralization capabilities. These results show the detailed comparison of each design variable with respect to their ability to fulfill the speech communication requirements. The study shows the limits and possibilities for acoustic design improvement of patient care-units at various stages of design.