Digital signal processing techniques are very important to the area of auditory neurophysiology since the auditory signals must be carefully controlled and because the data collection paradigms are frequently quite complicated. in this talk I shall describe a computer system that is jointly used by Bell Labs and Columbia Presbyterian Hospital. Key issues include methods for real-time data acquisition at 10-μsec rates while running a full operating system on the host computer, D/A and A/D hardware which produce less than 0.01% distortion for single tone signals, real-time linear system identification methods, and acoustic impedance measurement methods.