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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Medical Physicsarrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Medical Physics
Article . 1995 . Peer-reviewed
License: Wiley Online Library User Agreement
Data sources: Crossref
Medical Physics
Article . 1996
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Magnetic‐resonance imaging techniques for detection of elasticity variation

Authors: Fowlkes, J. B.; Emelianov, S. Y.; Pipe, J. G.; Skovoroda, A. R.; Carson, P. L.; Adler, R. S.; Sarvazyan, A. P.;

Magnetic‐resonance imaging techniques for detection of elasticity variation

Abstract

The relative success of manual palpation in the detection of breast cancer would suggest that a method for remote palpation resulting in a measurement of tissue elasticity could provide a diagnostic tool for detecting cancerous lesions deeper within the breast. This presumption is based in part on the excellent contrast between neoplastic and normal tissue due to the large (orders of magnitude) relative variation in the shear elastic modulus. By comparison, the bulk deformational modulus maintains the same value to within 20% for most soft tissues. A specific method of magnetic‐resonance imaging (MRI) which measures tissue displacements has been used in experiments with a phantom containing regions of increased Young's modulus as a demonstration. The spatial modulation of magnetization technique uses the displacement of a spatial grid pattern caused by spin saturation to track regional motion. Mathematical reconstruction of the distribution of elastic moduli is shown for select examples. Any modality, e.g., MRI, ultrasound, etc., which can detect local tissue motion with sufficient spatial resolution can be used and therefore the results presented here should give an indication of the utility of such motion tracking techniques to future measurement of tissue elasticity.

Country
United States
Keywords

SPATIAL DISTRIBUTION, Medicine (General), YOUNG MODULUS, Biophysics, Breast Neoplasms, Biophysical Phenomena, Magnetic resonance imaging, DIAGNOSTIC TECHNIQUES, Health Sciences, Humans, Ultrasonography, Cancer, PHANTOMS, Palpation, Tissue diagnostics, Phantoms, Imaging, ELASTICITY, MAGNETIC RESONANCE, Elastic moduli, 87.58.02, Models, Theoretical, MAMMARY GLANDS, Magnetic Resonance Imaging, Medical image contrast, Elasticity, Saturation moments, Treatment strategy, Spatial dimensions, Female, IMAGE SCANNERS, Medical imaging, NEOPLASMS

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
86
Top 10%
Top 1%
Top 10%
Related to Research communities
Cancer Research
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