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https://doi.org/10.1117/12.911...
Article . 2012 . Peer-reviewed
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Conference object . 2012
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Conference object . 2012
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A surface based approach for cortical thickness comparison between PiB+ and PiB- healthy control subjects

Authors: Vincent Doré; Pierrick Bourgeat; Jurgen Fripp; Oscar Acosta; Gaël Chételat; Cassandra Szoeke; Kathryn A. Ellis; +6 Authors

A surface based approach for cortical thickness comparison between PiB+ and PiB- healthy control subjects

Abstract

beta-amyloid has been shown to play a crucial role in Alzheimer's disease (AD). In vivo beta-amyloid imaging using [11C]Pittsburgh compound. (PiB) positron emission tomography has made it possible to analyze the relationship between beta-amyloid deposition and different pathological markers involved in AD. PiB allows us to stratify the population between subjects which are likely to have prodromal AD, and those who don't. The comparison of the cortical thickness in these different groups is important to better understanding and detect the first symptoms of the disease which may lead to an earlier therapeutic care to reduce neurone loss.

Country
Australia
Keywords

Surface based Approach, Positron emission tomography, Thickness measurement, beta amyloid, 610, Population statistics, PiB-PET images, Cortical thickness, Magnetic resonance imaging, Segmentation, Image processing, Medicine and Health Sciences, Alzheimers Disease, β-amyloid, Glycoproteins, Population analysis, Surface based ApproachAlzheimer's disease, β-amyloid, Brain, Statistical Population Analysis, Alzheimer's disease, Surface-based, Medical imaging, Mri

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
Green