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Fourier transform spectral interferometric coherent anti-Stokes Raman scattering (FTSI-CARS) microscopy

Authors: Sang-Hyun Lim; Bi-Chang Chen; Jiha Sung;

Fourier transform spectral interferometric coherent anti-Stokes Raman scattering (FTSI-CARS) microscopy

Abstract

A new multiplex CARS (coherent anti-Stokes Raman scattering) microscopy technique with a single ultrafast laser pulse is demonstrated. All the pump, Stokes, probe pulses are selected inside a single broadband cavity dumping Ti:Sapphire oscillator laser pulse. The measured CARS signal is a coherent sum of the resonant and non-resonant signals, leading to a complicated vibrational line shape due to the spectral interference. The resonant and non-resonant CARS signals, however, have different symmetries in the time domain due to the causality principle of the vibrationally resonant excitation. A new Fourier Transform Spectral interferometry (FTSI) is developed to extract the full complex quantity of the vibrationally resonant signal against the non-resonant one utilizing the different time symmetry. This method can generate Raman-like vibrational spectrum in a single experimental measurement, which can be readily applied to a vibrational hyperspectral imaging. Current sensitivity, available CARS window and application to hyperspectral vibrational microscopy are discussed.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
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