Nanofibers made from organic molecules such as para-hexaphenyl allow guiding of electromagnetic waves. Since they possess nanometric widths and heights but macroscopic lengths they represent the smallest possible optical waveguides. Recently, gain enhancement has been observed, pointing to possible applications as nanolasers. Owing to their self assembly growth mode on mica substrates the nanofibers posses well-defined morphology. In order to implement these aggregates into new optical devices or to enhance feedback and thus build up a resonator structure a defined cutting of the end faces is necessary. This article presents results from the first experimental studies in this direction. Irradiation with UV laser pulses of 193 nm at a fluence of 100 mJ/cm 2 removes the fibers completely without damaging the substrate. In addition, the fibers can be cut in any orientation relative to their long axes. The quality of the ablation process in terms of readsorbed debris and steepness of cutting is investigated by atomic force and scanning electron as well as fluorescence microscopy.