Two-dimensional fuzzy temperature controller was used in the system of inverter air-conditioner to control the room temperature. Self-adjustment PID fuzzy controller was proposed to realize real-time control function. V / F control mode was used to compensate with low voltage, the average sampling algorithm was proposed to implement SPWM waveform modulation. Finally, the feasibility of self-adjustment PID fuzzy controller was verified by simulation, the actual operation results had proved that self-adjustment PID fuzzy controller had reliable, good output waveform and small harmonic wave, which could meet operational requirements of inverter air-conditioner.