Single-cell photoacoustic thermometry
Copyright policy )Single-cell photoacoustic thermometry
A novel photoacoustic thermometric method is presented for simultaneously imaging cells and sensing their temperature. With three-seconds-per-frame imaging speed, a temperature resolution of 0.2°C was achieved in a photo-thermal cell heating experiment. Compared to other approaches, the photoacoustic thermometric method has the advantage of not requiring custom-developed temperature-sensitive biosensors. This feature should facilitate the conversion of single-cell thermometry into a routine lab tool and make it accessible to a much broader biological research community.
- University of Mary United States
- Washington University in St. Louis United States
- California Institute of Technology United States
570, Optical Phenomena, Single-cell thermometry, Microscopy, Acoustic, photoacoustic microscopy, Optical Devices, Hyperthermia, Induced, Thermometry, Body Temperature, Photoacoustic Techniques, single-cell thermometry, cell imaging, Neoplasms, Humans, Single-Cell Analysis, temperature sensing, HeLa Cells
570, Optical Phenomena, Single-cell thermometry, Microscopy, Acoustic, photoacoustic microscopy, Optical Devices, Hyperthermia, Induced, Thermometry, Body Temperature, Photoacoustic Techniques, single-cell thermometry, cell imaging, Neoplasms, Humans, Single-Cell Analysis, temperature sensing, HeLa Cells
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