AbstractObjectiveTo describe a case of congenital glaucoma in atiger (Panthera tigris).Animal StudiedAn 8‐month‐old intact female tiger wasreferred for suspected glaucoma of the right eye. The right eye was buphthalmicwith moderate episcleral injection, circumferential superficial cornealneovascularization, moderate corneal edema, and a fixed dilated pupil. Tapetalreflection was absent due to a mature cataract. Rebound tonometry under generalanesthesia revealed 70 mmHg and 21 mmHg in the right and left eye, respectively.ProcedureA trans‐conjunctival enucleation was performedand the globe was submitted for histopathology.ResultsHistopathology revealed a thin sclera, amorphousmaterial contouring an imperforate and hypoplastic iridocorneal angle, ahypoplastic lens with severe anterior‐posterior compression, subcapsularepithelial hyperplasia, and Morganian globules, and segmental moderate retinalatrophy. Periodic acid‐Schiff stain highlighted segmental dilations of theDescemet's membrane. Masson trichrome stain highlighted a pre‐irido collagenmembrane.ConclusionThe tiger's age and histopathologic findingsare consistent with congenital goniodysgenesis. This is the first known reportof congenital glaucoma in a tiger.