In Bacteria, the replicative DNA ligase is NAD‐dependent. However, some bacteria possess accessory ATP‐dependent DNA ligases (ADLs) which vary in size and domain organization. Phylogenomic analyses of bacterial ADLs reveal that types Lig B, Lig C and Lig D have descended from a common ancestor, while Lig E was transferred in a separate event, possibly from a bacteriophage. For details, see the article by Williamson et al. on pp. 274‐290 of this issue.

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Molecular Microbiology

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Molecular Microbiology

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In Bacteria, the replicative DNA ligase is NAD‐dependent. However, some bacteria possess accessory ATP‐dependent DNA ligases (ADLs) which vary in size and domain organization. Phylogenomic analyses of bacterial ADLs reveal that types Lig B, Lig C and Lig D have descended from a common ancestor, while Lig E was transferred in a separate event, possibly from a bacteriophage. For details, see the article by Williamson et al. on pp. 274‐290 of this issue.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2016 English Publisher:WileyJournal:Molecular Microbiology, volume 99 (issn: 0950-382X, eissn: 1365-2958,

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doi: 10.1111/mmi.13176

In Bacteria, the replicative DNA ligase is NAD‐dependent. However, some bacteria possess accessory ATP‐dependent DNA ligases (ADLs) which vary in size and domain organization. Phylogenomic analyses of bacterial ADLs reveal that types Lig B, Lig C and Lig D have descended from a common ancestor, while Lig E was transferred in a separate event, possibly from a bacteriophage. For details, see the article by Williamson et al. on pp. 274‐290 of this issue.

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