Regulatory T cells in oral squamous cell carcinoma
Copyright policy )Regulatory T cells in oral squamous cell carcinoma
Regulatory T cells (Tregs) play a critical role in modulating and maintaining immune homeostasis and tolerance. They accumulate in many types of tumors and play a critical role in tumor evasion of immune surveillance. Oral cancer is characterized by an increase in the number of infiltrating Tregs; however, the significance of this increase on the prognosis of oral cancer is controversial. This review focuses on the function of Tregs in oral squamous cell carcinoma and its implications on prognosis. We also discuss potential therapeutic strategies aimed at Tregs modification in oral SCC.
- Sichuan University China (People's Republic of)
- State Key Laboratory of Oral Diseases China (People's Republic of)
Carcinoma, Squamous Cell, Humans, Mouth Neoplasms, Lymphocyte Count, Prognosis, T-Lymphocytes, Regulatory
Carcinoma, Squamous Cell, Humans, Mouth Neoplasms, Lymphocyte Count, Prognosis, T-Lymphocytes, Regulatory
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