Effect of age and sex on bone markers in Chlorocebus aethiops raised in captivity
Copyright policy )Effect of age and sex on bone markers in Chlorocebus aethiops raised in captivity
AbstractBackgroundThe objective was to evaluate the procollagen type I N‐propeptide (PINP), osteocalcin (OC), β‐crosslaps (β‐CTX), and parathyroid hormone (PTH) in relation to age and sex of Chlorocebus aethiops in captivity.MethodsSeventy‐three monkeys were divided into four age groups: AG1 (juvenile); AG2 (young adult); AG3 (adult); and AG4 (senile). An electrochemiluminescence immunoassay with an Elecsys 2010 analyzer was used to determine the serum markers of bone.Results and conclusionsSex did not influence the results of the markers. However, the variables PINP, OC, and β‐CTX were negatively correlated with age (r = −0.643; r = −0.711; r = −0.488; P < 0.001, respectively), and PTH was correlated positively with age (r = 0.418, P < 0.001). The data obtained can be used as biomarkers of bone metabolism reference intervals in healthy C. aethiops in captivity.
Male, Hematologic Tests, bone formation markers of bone resorption markers, primates, Monkey Diseases, Osteocalcin, Age Factors, Cercopithecidae, Peptide Fragments, Bone Diseases, Metabolic, Sex Factors, Parathyroid Hormone, 616, Chlorocebus aethiops, Animals, Female, Bone Remodeling, Collagen, Biomarkers, Blood Chemical Analysis, Procollagen
Male, Hematologic Tests, bone formation markers of bone resorption markers, primates, Monkey Diseases, Osteocalcin, Age Factors, Cercopithecidae, Peptide Fragments, Bone Diseases, Metabolic, Sex Factors, Parathyroid Hormone, 616, Chlorocebus aethiops, Animals, Female, Bone Remodeling, Collagen, Biomarkers, Blood Chemical Analysis, Procollagen
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