
J Clin Hypertens (Greenwich). 2012;14:808–809. ©2012 Wiley Periodicals, Inc.New developments in cardiovascular translational sciences have significantly advanced our understanding of the endovascular biology of blood pressure. Reductions in vascular elasticity and vessel compliance of conduit arteries are key components of both ISH and SDH. Vascular changes from the matrix metalloproteinase family of enzymes are involved in arterial wall remodeling and vascular stiffness. This new translational information helps further our understanding of both ISH and SDH.
Translational Research, Biomedical, Matrix Metalloproteinase 9, Diastole, Systole, Hypertension, Humans, Endothelium, Vascular, Vascular Calcification
Translational Research, Biomedical, Matrix Metalloproteinase 9, Diastole, Systole, Hypertension, Humans, Endothelium, Vascular, Vascular Calcification
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