Update on long QT syndrome
Copyright policy )Update on long QT syndrome
AbstractLong QT syndrome (LQTS) is an inherited disorder characterized by a prolonged QT interval in the 12‐lead electrocardiogram and increased risk of malignant arrhythmias in patients with a structurally normal heart. Since its first description in the 1950s, advances in molecular genetics have greatly improved our understanding of the cause and mechanisms of this disease. Sixteen genes linked to LQTS have been described and genetic testing had become an integral part of the diagnosis and risk stratification. This article provides an updated review of the genetic basis, diagnosis, and clinical management of LQTS.
- Association of Universities and Colleges of Canada Canada
- Queen's University Canada
- Queens University Canada
Action Potentials, Prognosis, Long QT, QT Interval, Electrocardiography, Long QT Syndrome, Phenotype, Torsades de Pointes, Heart Conduction System, Heart Rate, Risk Factors, Humans, Genetic Predisposition to Disease
Action Potentials, Prognosis, Long QT, QT Interval, Electrocardiography, Long QT Syndrome, Phenotype, Torsades de Pointes, Heart Conduction System, Heart Rate, Risk Factors, Humans, Genetic Predisposition to Disease
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