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CHEMOSTERILANT ACTIVITY OF ANTINEOPLASTIC AGENTS

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1974 English Publisher:WileyJournal:Transactions of the New York Academy of Sciences, volume 36, pages 101-107 (issn: 0028-7113, eissn: 2164-0947,

Authors: Alexej B. Bořkovec; S. C. Chang; B. H. Braun;

doi: 10.1111/j.2164-0947.1974.tb01558.x

pmid: 4533843

CHEMOSTERILANT ACTIVITY OF ANTINEOPLASTIC AGENTS

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Abstract

AbstractThirty‐five antineoplastic agents were administered to adult house flies, Musca domestica L., by feeding or injection, and effects of the treatment on the flies' reproductive capacity were determined. For both sexes of the insect the most effective sterilants were alkylating agents; none of the hormonal drugs were active, but one antimetabolite sterilized females only. The category of miscellaneous antineoplastic agents contained several chemosterilants including l‐asparaginase, the only known enzyme with insect‐sterilizing effects.

Related Organizations

United States Department of the Interior
United States

Keywords

Male, Houseflies, Animals, Antineoplastic Agents, Chemosterilants, Female, Infertility, Female, Infertility, Male

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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average