
pmid: 7095956
ABSTRACT:Five patients are described with more or less continuous peeling of the skin aggravating in summer months. No family members are affected and consanguinity among parents of affected individuals is not seen. Characteristically the palms, soles, mucous membrane, and scalp are spared from shedding. Generally the patients look dirty and occasional erythema and vesiculation occur. Both sexes are affected equally. The disease does not start at birth and the onset may be delayed. Histopathologic examination shows subcorneal reparation of bulla formation without acantholysis. The stratum corneum appears very loose and shows little hyperkeratosis (or‐thokeratosis). Treatment is ineffective except mild keratolytics give cosmetic improvement. Etiology remains unknown. An autoimmune mechanism may be implicated. The authors propose the name ‘idinpathic deciduous skin’ for this distinct new dermatologic entity.
Adult, Male, Acantholysis, Adolescent, Humans, Female, Seasons, Epidermis, Child, Skin Diseases, Skin
Adult, Male, Acantholysis, Adolescent, Humans, Female, Seasons, Epidermis, Child, Skin Diseases, Skin
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