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Absorption of enteric and non‐enteric coated prednisolone tablets.

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1975 English Publisher:WileyJournal:British Journal of Clinical Pharmacology, volume 2, pages 317-320 (issn: 0306-5251, eissn: 1365-2125,

Authors: B Hulme; R Rault; V. H. T. James;

doi: 10.1111/j.1365-2125.1975.tb02777.x

pmid: 1233990

pmc: PMC1402595

Absorption of enteric and non‐enteric coated prednisolone tablets.

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Abstract

1. Relative rates of absorption of enteric and non‐enteric preparations of prednisolone were measured in five renal transplant recipients. 2. The absorption of the enteric coated preparation is delayed and the peak plasma concentration is much lower than that attained using the same dose of the uncoated material. 3. The therapeutic implications of these observations are discussed.

Related Organizations

Imperial College Healthcare NHS Trust
United Kingdom
St Mary's Hospital
United Kingdom

Keywords

Adult, Male, Adolescent, Hydrocortisone, Prednisolone, Blood Proteins, Binding, Competitive, Intestinal Absorption, Humans, Female, Tablets, Enteric-Coated, Protein Binding, Tablets

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	36
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%